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The new pheomelanin ring from the agouti-patterned hairs is a result of a heart circulation from ASIP phrase during the new hair growth, causing a button from eumelanin in order to pheomelanin development. To find the effectation of p.H587Y on the CORIN’s intent behind regulating ASIP regarding the tiger, we transfected HEK293 tissue that have tiger ASIP and you can/otherwise CORIN versions. No differences is actually thought of between the expression amount of wild-form of CORIN and also the p.H587Y mutant in the tissues (Contour 1F, leftover committee).

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